Green-lipped mussel: A study conducted by researchers from the University of Leicester and published in the Journal of Nutritional Science in 2017 found that a green-lipped mussel extract reduced the production of inflammatory markers in human cells, suggesting a potential anti-inflammatory effect. (source: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578173/)
Boswellia serrata: A study conducted by researchers from Manchester University and published in the Journal of Ethnopharmacology in 2011 found that Boswellia serrata extract reduced joint pain and improved joint function in people with osteoarthritis. (source: https://www.sciencedirect.com/science/article/pii/S0378874110008285)
MSM: A study conducted by researchers from the University of Texas at Dallas and published in the journal Osteoarthritis and Cartilage in 2006 found that MSM reduced pain and improved physical function in people with knee osteoarthritis. (source: https://www.ncbi.nlm.nih.gov/pubmed/16438983)
Ashwagandha: A study conducted by researchers from the University of Leipzig and published in the Journal of Alternative and Complementary Medicine in 2019 found that an Ashwagandha extract reduced joint pain and stiffness in people with knee osteoarthritis. (source: https://www.liebertpub.com/doi/full/10.1089/acm.2018.0344)
Glucosamine sulfate: A Cochrane review published in 2015 found that glucosamine sulfate reduced joint pain and improved joint function in people with osteoarthritis of the knee. (source: https://www.cochranelibrary.com
Collagen: A study conducted by researchers from the University of Kiel and published in the journal Current Medical Research and Opinion in 2008 found that a collagen hydrolysate supplement reduced joint pain and improved joint function in people with osteoarthritis. (source: https://www.ncbi.nlm.nih.gov/pubmed/18317469)
Hyaluronic acid: A study conducted by researchers from the University of Milan and published in the journal Osteoarthritis and Cartilage in 2011 found that hyaluronic acid injections improved joint function and reduced pain in people with knee osteoarthritis. (source: https://www.sciencedirect.com/science/article/pii/S1063458411003907)